아미오다론 투여용량 증량 후 발생한 급성호흡곤란증후군 1예   아미오다론 투여용량 증량 후 발생한 급성호흡곤란증후군 1예
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저자 오기종, 김창환, 강대길, 박명수, 심종섭, 박용범     
수록지 Soonchunhyang medical science   제18권 제2호  pp.155-158
발행사항 순천향의학연구소
발행년 2012
UCI G901:A-0003242178    공유
언어 kor
주제어 아미오다론, 급성호흡곤란증후군
초록 Amiodarone is a highly effective antiarrhythmic agent. It is commonly used to treat ventricular and supraventricular arrhythmias. However, amiodarone has been found to be associated with a variety of adverse effects. Amiodarone causes toxicity to organs such as lung, gastrointestinal tract, liver, eye, thyroid gland, skin, and neuromuscular system. Among these side effects, pulmonary toxicity is one of the most serious ones. The prevalence of amiodarone-induced pulmonary toxicity is not known precisely, but recent studies have reported that incidence rates range from 1% to 13%. The risk factors associated with the development of pulmonary toxicity are age, duration of treatment, cumulative dosage, history of cardiothoracic surgery, and use of high oxygen mixture. Amiodarone use has been rarely related to development of acute respiratory distress syndrome (ARDS), which is often in association with surgery or pulmonary angiography. We experienced a case of amiodarone-induced ARDS which developed after an increase of amiodarone dosage

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